Valaciclovir, also spelled valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster (shingles), and herpes B. It is a prodrug, which is converted to aciclovir in a persons body. Common adverse drug reactions (≥1% of patients) associated with valaciclovir therapy are the same as for aciclovir, its active metabolite, and include: nausea, vomiting, diarrhea and headache. Infrequent adverse effects (0.1–1% of patients) include: agitation, vertigo, confusion, dizziness, edema, arthralgia, sore throat, constipation, abdominal pain, rash, weakness and/or renal impairment. Rare adverse effects ( Valaciclovir belongs to a family of molecules first described and patented by Paolo Cornaglia Ferraris in 1982 (patents EP0077460 A2, CA1258149A1, DE3273785D1, EP0077460A3, EP0077460B1, US4567182). Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir (10–20%). 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If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice. Generic Valtrex Availability - Average Cost of Valtrex is $13.13; Click For More. Generic Product News - Pharmacy Times Valtrex is the brand name for valacyclovir, an antiviral drug used to treat infections caused by certain types of viruses. In adults, it's prescribed for shingles herpes zoster, cold sores. sildenafil dose Serious side effects of brand or generic Valtrex are fever, easy bleeding or bruising, redness of the skin it may not be related to chickenpox or herpes, vomiting. Jul 11, 2016. Valtrex, Acyclovir, and Famvir all treat symptoms of herpes outbreaks. Acyclovir can be used as a topical treatment for chickenpox as well.