Clinical question: Are clinical outcomes for dexamethasone equivalent to currently recommended corticosteroids for the treatment of children with mild to moderate asthma exacerbations? Background: National and international guidelines uniformly agree that administration of a systemic corticosteroid is appropriate for children hospitalized with mild to moderate asthma exacerbations. Based on available literature, a 2007 update to an expert panel report developed by the National Asthma Education and Prevention Program recommended prednisone, methylprednisolone, or prednisolone at 1-2 mg/kg daily in two divided doses (maximum 60 mg/day). Recent small studies have begun to examine the use of dexamethasone in acute asthma exacerbations. The longer half-life of dexamethasone enables shorter treatment regimens, which can improve compliance. Additionally, its taste is considered superior compared to currently recommended corticosteroids. Study designs: Two meta-analyses of randomized controlled trials (RCT). Synopsis: Both groups searched Medline for RCTs using the search terms “dexamethasone” and “asthma”; additional search terms included “decadron” and “status asthmaticus.” Limiting the search to a pediatric population was achieved by either using appropriate medical subject heading terms or by using an age limiter of ≤18 years of age. lasix dosage for water retention Last year my doctor prescribed me with Prednisolone to treat my rheumatoid arthritis. Both my knees are badly affected by the disease and it is a real suffering for me to move sometimes, after a long period without movement I can not easily get up and walk. I have to rub my knees, get used to the pain, and wait for the pain to fade away. It takes me about an hour to get out of my bedroom as I have to do many exercises before I stand up and can make first steps. The disease has been torturing me for more than seven years in general. I have tried many different medications - pills, ointments and injections. The effect is either none at all or just minor and temporary. With Prednisolone life got much easier and less painful for me indeed. Cialis email Table 1. Corticosteroid Dose Equivalents Equivalent Dose Steroid 1. Abimbola Farinde, PharmD, PhD Faculty, Columbia Southern University Abimbola Farinde, PharmD, PhD is a member of the following medical societies American College of Clinical Pharmacy, American Academy of HIV Medicine, American Pharmacists Association, Academy of Managed Care Pharmacy metoprolol identification Dexamethasone reduces inflammation and calms down an overactive immune system and is significantly more potent than prednisolone. Long-term use can adversely affect the way the immune system reacts. more Prednisone effectively controls inflammation and an overactive immune system but may not be. Online calculator to convert equivalent doses of corticosteroid compounds. Chrousos GP, "Chapter 39. Adrenocorticosteroids & Adrenocortical Antagonists" Chapter. Prednisone is prescribed for RA, Allergy, Crohn's Disease, Swelling, Ulcerative Colitis, Lupus, Asthma, Infection, Rash, Headaches, Itching, Joint Pain, Shortness of Breath, Hives and Acne and is mostly mentioned together with these indications. In addition, our data suggest that some patients take it for Fibromyalgia, although this is not an approved use*. between Dexamethasone and Prednisone in our records. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. Prednisone and Pain Dexamethasone and Pain Prednisone and Inflammation Prednisone and Methotrexate Dexamethasone and Revlimid Prednisone and Weight Gain Dexamethasone and Nausea Prednisone and Tiredness Dexamethasone and Multiple Myeloma Prednisone and Feeling Sick . My skin is an oily mess that I believe to be a result of the steriods on my sebaceous glands. 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