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Do not take this medication with any of the following medicines: -narcotic medicines for cough This medicine may also interact with the following medications: -alcohol -antihistamines for allergy, cough and cold -certain medicines for anxiety or sleep -certain medicines for depression like amitriptyline, fluoxetine, sertraline -certain medicines for seizures like phenobarbital, primidone -cholinesterase inhibitors like neostigmine, ambenonium, and pyridostigmine bromide -general anesthetics like halothane, isoflurane, methoxyflurane, propofol -local anesthetics like lidocaine, pramoxine, tetracaine -medicines that relax muscles for surgery -narcotic medicines for pain -phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine This list may not describe all possible interactions. They need to know if you have any of these conditions: -kidney disease -seizures -an unusual or allergic reaction to methocarbamol, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding Take this medicine by mouth with a full glass of water. Talk to your pediatrician regarding the use of this medicine in children. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. 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