Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and and certain forms of rheumatoid arthritis. Is plaquenil good for osteoarthritis Chloroquine resistance wiki Nov 13, 2012 All patients were started with initial combination therapy that consisted of 25mg/wk methotrexate MTX and 60 mg/day of prednisone tapered to 7.5mg/day over seven weeks. If patients achieved remission after 4 months, they were considered to be in early remission and could taper prednisone down to zero. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Aug 22, 2006 O'Dell J R, Leff R, Paulsen G, Haire C, Mallek J, Eckhoff P J. et al Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine or a combination of the three medications results of a two year, randomized, double‐blind, placebo‐controlled trial. Arthritis Rheum 2002 46 1164–1170.1170 Methotrexate made also be used for purposes not listed in this medication guide. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have low blood cell counts, a bone marrow disorder, weak immune system, liver disease (especially if caused by alcoholism), or if you are pregnant or breast-feeding. Methotrexate is usually given after other medications have been tried without successful treatment of symptoms. Some people have died after taking methotrexate every day by accident. Hydroxychloroquine with methotrexate combination steroid Treatment of rheumatoid arthritis with methotrexate and., Does anyone take methotrexate and hydroxychloroquine. - NRAS Cdc chloroquine resistance mapPlaquenil weight loss reviews A sensitivity analysis was conducted that included methotrexate MTX monotherapy with steroids, and hydroxychloroquine HCQ-sulfasalazine combination therapy as intensive therapy. Bootstrapping. Hydroxychloroquine is a safe and effective steroid-sparing.. Combination therapy with sulfasalazine and methotrexate is.. Rheumatoid Arthritis Drug Treatments Pros and Cons.. Methotrexate Combinations Methotrexate and Sulfasalazine. Of four studies identified, two compared the combination of methotrexate and sulfasalazine in a parallel approach to monotherapy with either sulfasalazine or methotrexate. Both studies were double-blind, randomized controlled trials. Clinical practice guidelines recommend use of combination DMARDs such as hydroxychloroquine plus methotrexate for patients with a disease duration less than 6 months and moderate disease activity and poor prognostic features and is an option for high disease activity and poor prognostic features. Can SLE be treated with plaquenil alone if caught early. I am somewhat of an atypical case on a plaquenil trial. more Can SLE be treated with plaquenil alone if caught early. I am somewhat of an atypical case on a plaquenil trial. no steroids yet.