It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases. Hi, I started taking Plaquenil on June 24th and for the last four or 5 days have had horrible itching. My Rhuemy told me to stop taking it until all itching symptoms were gone, then wait another week and start up again with 1 pill (200mg) a day instead of 2 pills. Hydroxychloroquine cardiac side effects What are the side effects of taking hydroxychloroquine Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine is a relatively well tolerated medicine. The most common adverse reactions. reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking hydroxychloroquine with food. Hydroxychloroquine may also cause itching in some people. All medicines may have some side effects. Hi, I started taking Plaquenil on June 24th and for the last four or 5 days have had horrible itching. No rash just all over itching. My Rhuemy told me to stop taking it until all itching symptoms were gone, then wait another week and start up again with 1 pill 200mg a day instead of 2 pills. I have been on Plaquenil for 11 months now without the return of any itching. Has anyone else experienced this infernal itch and what was your outcome. Thanks I had terrible itching for a few weeks but I noticed I felt so much better after about 6 to 7 weeks. The itching stopped without lowering the dose from 400mg. Hydroxychloroquine side effects itching Hydroxychloroquine Side Effects -, Medicines for the Prevention of Malaria While Traveling. Can hydroxychloroquine stop bone graft osseointegrationHydroxychloroquine sulfate adverse reactionsPlaquenil visual field lossSide effects after stopping plaquenilHigh cost of hydroxychloroquine These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Itching From Plaquenil DailyStrength. Hydroxychloroquine Uses, Dosage & Side Effects -. This study is created by eHealthMe based on reports of 57,706 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced pruritus. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.