The pharmacist said there wont be any danger just stopping it. Has anyone gone off the plaquenil and what happened? I was put on Plaquenil for RA as I was being dx for lupus. My rhuemy wants me to stop every time I have an infection. Best of luck, Creekbank My mom said she read that plaquenil is mainly used for the discoid lupus and people with the joint pain. Right now my hips are the only thing that is really bothering me my knees are now starting to act up..... Chloroquine treatment autophagy Plaquenil losing weight Mental side effects of plaquenil Hydroxychloroquine and rheumatoid arthritis Hi, I JUst wanted to let you know that Plaquenil, and other lupus meds can be rough on your stomach.so in the beginning than long term. My doctor reccomended that I eat 100 calories at least prior to taking Plaquenil and Naproxen. I was prett nauseous the frist 2 weeks on these meds, but over time it diminished. Apr 10, 2019 Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Hi, for anyone that's been on plaquenil long term i've been on more than 2 1/2 years, have you had any moderate to bad flares or flares that dont' seem to go away while taking this med? There is no taper needed or withdrawal, but if it has been helping you, you may have increased symptoms by the time you go for your next appointment. If so, you would likely be able to get a prescription from that doctor for one month's supply to tide you over. I have only taken it once, so I am not sure what the results will be. I stopped mine and went into a life threatening flare - I would call your PCP to get a refill You may be fine or not- depends on if your illness has been lurking in the background waiting for an opportunity to launch an attack Louters, I went to see a new rheum and he took me off the Plaquenil to see what symptoms would show. I agree with poobie and would call your pcp to get a refill if possible. Taking plaquenil for lupus Lupus remission Lupus Foundation of America, Plaquenil Uses, Dosage & Side Effects - Plaquenil immune systemPlaquenil dosage 400 mg I was put on Plaquenil for RA as I was being dx for lupus. I am very mild. My rhuemy wants me to stop every time I have an infection. When it is gone she said I can resume at my own pace. Take into consideration I only take Plaquenil and ibuprofen 800mg. My symptoms came back after two weeks of being off it. Stopping Plaquenil - General Discussion - Life With Lupus. Immune & Autoimmune - Lupus Flares While Taking Plaquenil. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. How does Plaquenil work? Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as.