Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Side effects of plaquenil on the cornea Chloroquine injection use Chloroquine definition, a synthetic substance, C18H26ClN3, used chiefly to control malaria attacks. See more. Chloroquine phosphate comes as a tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose. Chloroquine CQ is a lysosomotropic antimalarial drug that neutralizes. Chloroquine is still the drug of choice for sensitive malaria parasites although ACTs. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Define chloroquine What is chloroquine? Trump, Elon Musk tout possible., Chloroquine MedlinePlus Drug Information Hydroxychloroquine sulfate overdose Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline. Chloroquine drug Britannica - Encyclopedia Britannica. Chloroquine - an overview ScienceDirect Topics. Chloroquine dictionary definition chloroquine defined. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. It does not produce a radical cure because it has no effect on the exoerythrocytic stages; chloroquine-resistant strains of P. falciparum have developed in Southeast Asia, Africa, and South America. It is also used for hepatic amebiasis and for certain skin diseases, for example, lupus erythematosus and lichen planus.