In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil hydroxychloraquine Plaquenil hyperpigmentation treatment Chloroquine dosage Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Misinterpretation of Humphrey visual field HVF findings in patients utilizing hydroxychloroquine HCQ can lead to delay in diagnosis of retinal toxicity. Early retinopathy has been defined as an acquired, persistent paracentral scotoma visualized on automated visual field testing without any observable fundus changes. The visual field test is among the most important tests to learn to interpret as you begin your career in ophthalmology. Learn about the top 5 most common fields. Macular diseases including plaquenil toxicity exams also need 10-2. HVF 30-2. Generally, we order this for neuro patients. It has a wider angle and can capture peripheral field. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Visual field testing for plaquenil toxicity Plaquenil therapy and eye exams. - Eye Care - MedHelp, Humphrey visual field findings in hydroxychloroquine toxicity. Chloroquine cell signallingChloroquine corneaStopped taking plaquenil Very early on toxicity is usually asymptomatic detected only by a spectral domain optical coherence tomographer and a macular visual field test. When allowed to progress plaquenil toxicity causes the loss of visual acuity, peripheral vision and night vision. Risk Factors for Toxicity • use of drug longer than 5 years • liver or kidney disease Plaquenil Examination - McKinney Eye Works. How to interpret visual fields 5 most common patterns.. Humphrey visual field findings in hydroxychloroquine toxicity. Visual field testing Automated VF testing can be valuable in detecting early changes in the retina and, in a reliable patient, can be the most sensitive test to detect such changes Figure 2. 3,4 Standard 10-2 white SITA testing with pattern deviation is recommended for screening the central and parafoveal areas. Abnormal test is the visual field test, you may be asked to repeat it to make sure of the results. You will be told if any other tests are necessary and when you should be screened again. In cases of possible retinopathy, you will be recommended to continue taking 8 9 Macular Society Eye screening for patients taking hydroxychloroquine The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients still experience permanent vision loss resulting from hydroxychloroquine retinopathy due to improper dosing of the drug and improper screening.