Hydroxychloroquine induced pigmentation

Discussion in 'Northwest Pharmacy Canada' started by hardwj, 21-Feb-2020.

  1. BingoS Moderator

    Hydroxychloroquine induced pigmentation


    In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent.

    Hydroxychloroquine and neonatal lupus Hydroxychloroquine retinal toxicity retina replacement

    Hydroxychloroquine-induced Hyperpigmentation of the Skin. J Rheumatol. 2015;421135-6. Jallouli M, Frances C, Piette JC, Huong du LT, Moguelet P, Factor C, et al. Hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus a case-control study. Home August 2013 - Volume 19 - Issue 5 Hydroxychloroquine-Induced Hyperpigmentation. Log in to view full text. If you're not a subscriber, you can An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B.

    Download PDF Many systemic medications may cause retinal toxicity. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended.

    Hydroxychloroquine induced pigmentation

    Persistent cutaneous hyperpigmentation due to., Hydroxychloroquine-Induced Hyperpigmentation JCR Journal.

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  5. Hyperpigmentation has been suggested as a marker of increased risk for retinopathy4 and is gener-ally reversible after cessation of HCQ within 2–6 months. Hyperpigmentation in our patient was limited to the lesions of GA which may be similar to the type of minocycline induced pigmentation seen in acne scars 5 and needs further investigation.

    • Hydroxychloroquine induced cutaneous pigmentation a unique pattern.
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    Apr 30, 2018 Drug-induced pigmentation is not generally associated with any systemic toxicity and thus has an excellent prognosis. With some exceptions, pigmentation is usually reversible and slowly fades with discontinuation of the drug. We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female case 1 and a 78-year-old female case 2, both receiving 400 mg per day. The incidence of hydroxychloroquine-related hyperpigmentation in patients with systemic lupus erythematosus is about 7%, but unlike hydroxychloroquine-related retinopathy, there is no clear association with cumulative dose or duration of use.1 Roughly half of cases occur in the first five years of treatment.

     
  6. ukdiploms User

    Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Hydroxychloroquine Side-effects, uses, time to work Protecting your eyesight when taking Plaquenil Lupus. How is plaquenil hydroxychloroquine used to treat lupus?
     
  7. Macular Pucker Diagnosis and Treatment BrightFocus Foundation These can include color photographs of the retinas, and important cross-section photos of the retina taken by a process called optical coherence tomography OCT. The OCT shows the extent of retinal scar formation and retinal distortion caused by traction from the scar tissue. Treatment Non-Surgical Interventions Macular Pucker

    Macular Pucker National Eye Institute