Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Hydroxychloroquine side effects fluid retention Chloroquine phosphate toxic Chloroquine’s anti-parasitic activity stems from its ability to bind heme, resulting in disruption of membrane function and cell lysis. Chloroquine also displays antiviral, immunosuppressive, and anticancer activities. Chloroquine inhibits the replication of many viruses and also inhibits production of IL-6 and TNF-α. Chloroquine diphosphate Catalog No. T0194 CAS 50-63-5 Synonyms Aralen phosphate, Chingamin phosphate Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine diphosphate stock Chloroquine diphosphate CAS50-63-5 Antimalarial drug For Research., Chloroquine diphosphateATM/ATR activatorbuy chloroquine. Life extension chloroquineHow effective is plaquenilSulfasalazine vs plaquenilHydroxychloroquine dose for ra Chloroquine DiphosphateMarket report provides the systematic outlook of the industry by considering features such as market growth, consumption volume and Chloroquine Diphosphate market trends. Chloroquine Diphosphate Market 2020 Top Companies.. Chloroquine - FDA prescribing information, side effects and uses. Chloroquine - Wikipedia. Chloroquine is commonly used to study the role of endosomal acidification in cellular processes 2, 3, such as the signaling of intracellular TLRs. Moreover, Chloroquine inhibits autophagy as it raises the lysosomal pH, which leads to inhibition of both fusion of autophagosome with lysosome and lysosomal protein degradation 4. Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy 1. Chloroquine diphosphate has been reported as an adjuvant for radiation and chemotherapy for inducing cell autophagy to anti-cancer cells proliferation or metastasis 2. Selected citations for Chloroquine diphosphate include 2 Citations Showing 1 - 2 Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy.