To get around that, it is best to leave 4 hours between taking either of them. The doctor's indication on my Plaquenil packet does say not to take antacids for 2 hours within taking Plaquenil but I didn't realise that calcium tablets have a similar effect. Does hydroxychloroquin protext against malaria Chloroquine retinopathy Apo hydroxychloroquine side effects As far as I know the advice is to make sure that antacids and Plaquenil are taken at least 4 hours apart. If they are taken together - effectiveness decreases but 4 hours apart is OK. Never do tomorrow what you can put off till the day after tomorrow! This can be a normal side effect from the plaquenil and it usually lasts a couple of weeks until your body adjusts to it. Try to stick it out, continue taking the compazine but know that that med itself causes drowsiness. You may want to ask for Zofran which doesnt make you as you take it before bed. To get around that, it is best to leave 4 hours between taking either of them. The doctor's indication on my Plaquenil packet does say not to take antacids for 2 hours within taking Plaquenil but I didn't realise that calcium tablets have a similar effect. ), this is part of the reason I will not touch steroids Brilliant, thank you for letting me know. I find the whole ' Calcium' thing confusing, I have too much calcium in my body which can in turn affect Raynauds but my bones, nails, teeth r so weak, it's hilarious, they break at the slightest thing (& no, I'm not just talking about my nails either! Can i take antacids while taking plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Side Effects Go Away? DailyStrength Plaquenil side effects acneHydroxychloroquine with lamotrigine Plaquenil is VERY hard on the stomach. I take mine with prescription antacids to protect my stomach. Can I take Plaquenil at night? - Sarcoidosis - Inspire. Plaquenil and Calcium/Vit D For those of you who.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Plaquenil and Pepcid. Support Forums. I wonder if this is a personal opinion about taking it earlier than the plaquenil or maybe something we need to check into more. Some of this stuff is an antacid and some is a proton pump inhibitor. I would listen to the pharmacist because they know more about the meds than the docs do. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea.