I was diagnosed with discoid lupus 18 years ago and was prescribed Plaquenil, which I have taken since then. In October 2012, I was also diagnosed with Sjogrens Syndrome but, as I was already taking Plaquenil, was advised the treatment was the same for Sjogrens. Plaquenil drugs com Will plaquenil help irritable bowel syndrome Hydroxychloroquine decrease inflammation Aug 02, 2010 My Absolute Neutrophils good indicator of immune system function didn't get suppressed to a NORMAL range until I increased the Plaquenil to 600mg/day while still taking the Prednisone. In addition, my white blood cell count was still within a normal range. Expand. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. The main inclusion criteria were age 18 years, serum hemoglobin level ≥10 g/dL, white blood cell count ≥4000/mL, plasma platelet count in the range of 150.000–400.000/mL, glomerular filtration rate ≥70 cc/mL, serum Aspartat aminoteransferase AST and Alanin Aminoteransferase ALT levels less than 1.5-times of the upper normal limit. From research I have done online, I gather that low white cell count can also be a symptom of the Sjogrens in itself. At a recent medical with my doctor, blood tests were taken and I had a call a couple of days later telling me to stop taking g Plaquenil immediately as I have a very low white cell count and that it is sometimes a side effect of Plaquenil. Plaquenil and low white blood count Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Long-Term Side Effects of Plaquenil for Rheumatoid. Hydroxychloroquine sulfate highHydroxychloroquin safetyPlaquenil tooth decayLow dose naltrexone and plaquenilHydroxychloroquine retinal toxicity risk factors Druginformer Identified Side Effects White blood cell count. Posted By Anonymous in on August 17, 2010 @ am “ Side Effects low white blood cell count I absolutely loved Plaquenil. I had saliva and the swelling in my joints was gone. Hydroxychloroquine Sulfate White Blood Cell Count Reports.. The effect of hydroxychloroquine on glucose control and insulin.. Plaquenil and White blood cell count decreased - eHealthMe. Low White Blood Cell Count Information Including Symptoms, Diagnosis, Treatment, Causes, Videos, Forums, and local community support. Find answers to health issues you can trust from Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Dugan on plaquenil and low wbc This drug can effect the bone marrow and make the white blood count and platelets low. Your doctor may want to stop this medication, but don't stop it till you talk to the doctor. Good luck!