What is chloroquine resistance

Discussion in 'Health Canada Drug Database' started by narciruss, 14-Mar-2020.

  1. Karandache Well-Known Member

    What is chloroquine resistance


    Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. Oct 01, 2018 Chloroquine resistance is widespread in P. falciparum and is reported in P. vivax. Before using Chloroquine for prophylaxis, it should be ascertained whether Chloroquine is appropriate for use in the region to be visited by the traveler. Chloroquine became the drug of first choice in malaria therapy for more than two decades until resistance limited the use of the drug. The resistance is correlated to point mutations in the gene pfcrt 26. The gene codes for a transporter PfCRT.

    Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria.

    What is chloroquine resistance

    Chloroquine and Proguanil - Superdrug Health Clinic, Chloroquine - FDA prescribing information, side effects and uses

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  4. Chloroquine is used to prevent and treat malaria. It is also used to treat liver infection caused by protozoa extraintestinal amebiasis. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito.

    • What is Chloroquine Phosphate? - GoodRx.
    • Chloroquine - an overview ScienceDirect Topics.
    • Lack of Evidence for Chloroquine-Resistant Plasmodium falciparum..

    Chloroquine resistance is widespread and, at present, is particularly prominent in various parts of the world including sub- Saharan Africa, Southeast Asia, the Indian subcontinent, and over large portions of South America, including the Amazon basin 1. Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen.

     
  5. AntonFisher XenForo Moderator

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. The Risk of Retinal Toxicity with Plaquenil Let me tell you what weaning down from Plaquenil is like. Ask the Expert Plaquenil and Sjögren’s
     
  6. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Common and Rare Side Effects for Chloroquine Oral Chloroquine Uses, Side Effects & Warnings - Chloroquine Oral Route Side Effects - Mayo Clinic
     
  7. MemiteteSow Guest

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  8. James B. Guest

    Will you have Raynaud's phenomenon with Hydroxychloroquine sulfate. Raynaud's phenomenon is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 40-49 old, also take medication Synthroid, and have Multiple myeloma

    Re Plaquenil and Secondary Raynaud's - Health, Medicine and Natural.