You see, about two years I was diagnosed with one mixed connective tissue disorder. Good friend recommended me some Plaquenil drug for this and I was just wondering has anyone used it and what were the effects. I'm very sorry that you have developed this unpleasant condition. I had the plaque-type rash on upper arms, back and face. I talked with my sister about this because few years back she had the same problems like you now. Plaquenil pill doses Does plaquenil help discoid lupus Plaquenil toxicity optos Lupus arthritis causes pain, stiffness, swelling, tenderness and warmth in your joints. The joints most often affected are the ones farthest from the middle of the body, such as fingers, wrists, elbows, knees, ankles and toes. General stiffness upon awakening, which gradually improves as the day goes on, is a key feature of lupus arthritis. Swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Osteoporosis. Cause of sudden swollen ankles. I've just been wondering if it has anything to do with my stopping Plaquenil about a month ago.that's about the same time the swelling started. Also, sjs causes non destructive arthritis and can cause swelling also. It is still arthritis and swelling is part of that. However, if you are really sloshing. It worked so well for her that she almost forgot she had the disease. I was using one drug and topical cream for my skin changes and it didn’t help that much. Just recently I started to notice that my feet began to swell. She was also using this Plaquenil and it has changed her life completely. Can plaquenil cause ankle swelling Rheumatoid Arthritis Signs, Symptoms, and Complications, Will you have Swelling with Plaquenil - eHealthMe Stopped taking plaquenil It can also result in immobility and deformity of the wrists, fingers, ankles, and feet. There are a variety of symptoms that result from rheumatoid arthritis. However, one particularly problematic symptom is the development of swelling in the feet and ankles. This symptom can appear in both feet and will generally affect the same joints in. Rheumatoid Arthritis Swollen Feet & Ankles Atlanta. Cause of sudden swollen ankles. DailyStrength. Plaquenil Side Effects Common, Severe, Long Term -. It can cause major swelling in a knee and your ankle could be a result of that or a result of limping on the knee. eye swelling is also a major symptom of reiter's syndrome. i think it's caused by an infection it can be a number of different types of infections, including stds but also different bacterial and parasitic infections. Plaquenil and Severe Ankle Pain. Support Forums. I had gone into a Rheum who tested me and put me immediately on Plaquenil. My symptoms became worse, sores in mouth, rash on chest, stomach issues, hair falling out and for some reason severe ankle pain. None of these symptoms were present prior. Plaquenil swelling and rash on ankle joints. Premium Questions. Joint pain, chest pain, unknown autoimmune disorder. Taken Plaquenil and Prednisone. Normal CRP. Can Plaquenil cause rashes on the body? MD. of meds for the rash that will not go away. could this be from the plaquenil that I am taking ? Help.