This is not intended to be a complete catalog of all possible ocular side effects from different medications. Instead, it lists common ocular side effects, or those which deserve special mention. Effects of plaquenil on skin Hydroxychloroquine in pregnancy Fundus autofluorescence in hydroxychloroquine toxicity Is chloroquine sulfonamides Jun 30, 2015 Retinal damage. Plaquenil may cause irreversible damage to the retina the back of the eye where vision is created. You are required to have an eye exam before taking Plaquenil, then a follow-up as often as needed while taking Plaquenil. Tell your healthcare provider right away if you have some or all of the following symptoms. Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Annual comprehensive eye examinations are recommended by the American Optometric Association for people with lupus, especially for anyone taking Plaquenil. As a precaution, people treated with Plaquenil should get a baseline eye exam before or soon after starting the drug and visit an eye doctor ophthalmologist annually. Included are over-the-counter medications and prescription medications. These sections are not intended to replace the professional examination and diagnosis by a physician, and they are presented here purely for informational purposes. Just because a drug is not listed here does not mean that it does not have any possible ocular side effects. Plaquenil and touble eye focus How Do Ophthalmologists Look for Plaquenil Damage? - American., Rx Side Effects New Plaquenil Guidelines and More - American Academy. Order chloroquineSide effects of stopping plaquenil cold turkeyPlaquenil tabs Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The Risk of Retinal Toxicity with Plaquenil. How lupus affects the eyes Lupus Foundation of America. Who Is at Risk for Vision Loss with Plaquenil? - American.. The Link between Eye Problems and Lupus Medications. Many eye problems in patients with lupus originate from the drugs doctors use to treat lupus itself. Three groups of medications prescribed for lupus patients are immunosuppressive drugs such as methotrexate and mycophenolate, antimalarials such as hydroxychloroquine Plaquenil®, and. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An ophthalmologist eye specialist often can detect changes in the retina that suggest toxicity before serious damage occurs. Therefore, regular eye examinations, even when there are no symptoms, are mandatory. Your eye care provider can examine the macula and detect subtle changes before you begin to notice any symptoms of problems. As a result, all patients taking plaquenil should have an examination approximately every six months. The macula should be examined through a dilated pupil. The incidence of Plaquenil related macular problems increases.