In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. Msds chloroquine phosphate Hydroxychloroquine sulphate pregnancy Treatment/Plaquenil. Support Forums. I find I am really starting to suffer from lots of aches and pains and extreme fatigue. I'm so tired I have fallen asleep at my desk at work. I am only a few years older than you and have been on plaquenil for a year, it does help me with fatigue, it helps with my aches and pains and it has. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, I've never heard of anyone having fatigue from plaquenil since I've been on these forums. Usually, auto immune diseases and the conditions that go with them such as anemia and vitamin deficiencies cause the fatigue. “I had been very active my whole life, and the fatigue just knocked me flat. Utterback, Ph D, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Plaquenil and extreme fatigue Ask the Expert Plaquenil and Sjögren’s, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Aralen dosage for lupusHow much chloroquine phoshate for 300 gqallonsCan i take eyebright with plaquenilDoes plaquenil cause melasma Please I need to find out if anyone who has taken plaquenil has experienced back and hip pain. I started in Oct of 2011 taking 200 mg of plaquenil once a day. In April of 2012 I started taking 400 mg 2 x's a day. I did start to notice that I was having pain when I tried to sleep at night. Mostly in my arms hands and ankles. Plaquenil and pain" Rheumatoid Arthritis Community.. Is extreme fatigue a side effect of Plaquenil?. Patient Information on Lupus Fatigue HSS Rheumatology. Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Inflammation is the most common reason for muscle pain and aches. Any time that major inflammation exists "strep" throat, hepatitis, cancer, lupus, acute heart attack, etc. signs and symptoms often include fevers, sweats, chills, fatigue, weight loss, and various muscle aches, pains and weakness. Although a mystery, some doctors believe that lupus fatigue can be related to the overactive nerve signals and imbalances that are associated with the disease fibromyalgia. Since one third of lupus individuals have fibromyalgia, it is no surprise that extreme fatigue comes with it.