It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine autophagy 293t Chloroquine maculopathy ppt OBJECTIVE To assess the efficacy of hydroxychloroquine treatment of morphea. METHODS We conducted a retrospective study of 84 patients who had morphea and were treated with hydroxychloroquine monotherapy for at least 6 months at our institution from 1996 through 2013. The median times to initial and maximal responses were assessed. Localized scleroderma, or morphea, is a chronic disease that causes a thickening and induration of the skin. For plaque type morphea, the treatments include super-potent corticosteroids and calcipotriol. For the more generalized forms, as well as the linear forms, UVA is currently the best therapeutic modality. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine scleroderma Scleroderma Treatment General – Standard - Scleroderma Education Project, Treatment Options For Localized Scleroderma Do i need hydroxychloroquine with methotrexatePlaquenil freeHalf life of plaquenil I was prescribed Hydroxychloroquine last year by the team at the Royal Free Hospital. After taking it for a few days, I had really bad side effects as I couldn't tolerate the dose. Although I was on the lowest dose that they usually prescribe, I have been advised to take half the tablet for five days a week instead as I am quite thin. Hydroxychloroquine I was prescribed. - Scleroderma & Ray.. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine? - UK Scleroderma - Sclero Forums. Immunosuppressants fall under a category of drugs referred to as DMARDs Disease-Modifying Anti-Rheumatic Drugs. ISN. Scleroderma Treatments and Clinical Trials ISN. Effect of disease-modifying anti-rheumatic drugs DMARDs on bone structure and strength in psoriatic arthritis PsA patients. I visited my rheumy today and he has prescribed plaquenil to help treat my scleroderma. I have limited CREST scleroderma. My symptoms seem to have worsened over the past couple of months, mainly, extremely. Also see Overview of Skin Involvement, What is Scleroderma? and Types of Scleroderma Some medications, such as plaquenil and minocycline, can cause permanent dark skin plaques, which resemble black and blue marks similar to morphea scleroderma. Cosmetically, pigmentation differences can be covered up with corrective cosmetics, such as Dermablend.