Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. What is chloroquine resistance Hydroxychloroquine methotrexate drug interactions Chloroquine nightmares Buy aralen online Hydroxychloroquine Plaquenil Chloroquine Aralen Quinacrine Atabrine What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. Cutaneous lupus erythematosus encompasses a wide range of dermatologic manifestations, which may or may not be associated with the development of systemic disease. Cutaneous lupus is divided into several subtypes, including acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus. Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine cutaneous lupus Coronavirus Update Access to. -, Cutaneous Lupus Erythematosus Diagnosis and treatment Hydroxychloroquine rashChloroquine transfection mechanismWeaning off of plaquenil Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy. Chloroquine Side Effects Common, Severe, Long Term.. How is plaquenil hydroxychloroquine used to treat lupus?. Chloroquine DermNet NZ. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Alternative therapies, anecdotal reports, and small, open-label trials as reported by. Adverse cutaneous reactions to hydroxychloroquine are more common in patients with dermatomyositis than in patients with cutaneous lupus erythematosus. Pelle MT1, Callen JP. Author information 1Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, USA. Chloroquine, which was first approved in 1949, and hydroxychloroquine, which was approved in 1955, are often prescribed to people diagnosed with rheumatoid arthritis, lupus, or to treat malaria.