She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Plaquenil nail discoloration Hydroxychloroquine monitoring eye For those of you that don't know, plaquenil can cause a certain kind of retinopathy/maculopathy in the eyes if your dose is too high because the drug builds up in your system. It can cause blindness. So when I had the photography done the optometrist had a concerned look on her face and proceeded to take 17 more photos of my retinas. HealthDay—Hydroxychloroquine HCQ blood levels are useful in predicting retinopathy among patients with systemic lupus erythematosus SLE, according to a study published online Sept. 18 in. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenil and diabetic retinopathy Plaquenil Las Vegas Diabetic Retinopathy Wellish., Hydroxychloroquine blood levels predict retinopathy risk. Artemisinin and chloroquine structure Hydroxychloroquine HCQ is an antimalarial agent that is commonly used to treat rheumatoid arthritis RA and systemic lupus erythematosus SLE. The present report documents a case of hypoglycaemia due to HCQ in a patient with SLE and diabetes mellitus type 2, in which the HCQ completely replaced the need for daily subcutaneous insulin. Hydroxychloroquine a diabetic drug in disguise?. Hydroxychloroquine-Induced Retinal Toxicity - American.. Hydroxychloroquine toxicity - EyeWiki. With diabetes, the blood vessels supplying the retina and other parts of the eye become fragile and compromised. The retinopathy related to plaquenil use is actually from a kind of deposit that forms on the surface of the retina and in advanced cases, takes a "bulls-eye" shape that can be seen on exam. Jun 21, 2012 Some resources about Plaquenil hydroxychloroquine and retinopathy Screening for Hydroxychloroquine Retinopathy 08/2011 This is the American College of Rheumatology Position Statement Hydroxychloroquine Plaquenil is a commonly used medication in the management of various rheumatic diseases. Retinal Physician® Therapeutic and Surgical Treatment of the Posterior Segment delivers in-depth coverage of the latest advances in AMD, diabetic retinopathy, macular edema, retinal vein occlusion as well as surgical intervention in posterior segment care. It reaches both retinal specialists and general ophthalmologists with practical insight regarding current and future treatment strategies in medical and surgical retina care.