Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine and sun What are the most common side effects of plaquenil Hydroxychloroquine cause urinary infections Hydroxychloroquine sulfate tablets uses Plaquenil eye problems. Posted by Wesbig @wesbig, Jul 25, 2016. I was wondering if anyone experienced blurry vision on Plaquenil. I have been on Plaquenil for about a month. Every now and then I notice some of the words on the television are blurry, then there are other times my eyes are fine. Should this be a big concern? Taking Hydroxychloroquine develop toxicity2 It’s rare for side effects to occur with Plaquenil if the medication is dosed properly Side effects Blurred vision, bull’s eye maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3 On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil toxicity and eyes Hydroxychloroquine retinopathy A review of imaging, Early Plaquenil Toxicity Detected without Bull’s Eye. Plaquenil side effects eyes symptomsPlaquenil and doxycycline interactionChloroquine lupus side effectsHydroxychloroquine tablets ip hcqs 200 Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine-Induced Retinal Toxicity - American.. Plaquenil, Toxicity and My Eyes - This Lupus Life. Plaquenil Toxicity Plaquenil hydroxychloroquine is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis. After prolonged use, it can sometimes damage the macula and cause central vision loss. Typically, the macula loses its orange pigment, giving the appearance of a bullseye. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula.