Newer studies have preferred practice protocols be changed to using spectral-domain OCT technology as the main screening device for detection of early retinal changes in plaquenil toxicity. The patient reported that she was in reasonably good health despite a long-term history of lupus. Plaquenil class Hydroxychloroquine logp Hydroxychloroquine nursing interventions Quinine plaquenil Visual fields. The subjective component to HCQ retinopathy screening is an automated visual field testing the central 10° of vision. The earliest signs of HCQ retinopathy on a central visual field may present as a cluster of paracentral points with decreased sensitivity. These points may be only mildly depressed. Symptoms and SignsMechanism of ToxicityMedication DosageRisk For ToxicityMonitoring GuidelinesConclusion History of Present IllnessOcular ExaminationDiscussionFull Clinical History and CourseDifferential Diagnosis In addition to medication for her lupus, she was also being treated with glyburide for diabetes and an unkown medication for hypertension. She was taking 200 milligrams of plaquenil per day to treat her lupus and had been on this dose level for the past twenty years. Plaquenil maculopathy visual field Plaquenil - FDA prescribing information, side effects and uses, Hydroxychloroquine-Induced Retinal Toxicity - American. Buy aralen medicationWhat is chloroquine aralenChloroquine resistant falciparum malaria treatmentHydroxychloroquine and dormancyHow long chloroquine tablets is good after expiration date Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that New Plaquenil Guidelines -. Hydroxychloroquine Plaquenil Toxicity and.. Hydroxychloroquine Retinopathy Still Alive and Well - The Rheumatologist. OverviewPresentationPathophysiologyDiagnosisTreatmentPrognosis Side effectsManagementGoalsMechanismPrognosisPathophysiologyToxicityPreventionInteractionsGeneticsPurposeMedical usesAnalysisResearchDiagnosisSecurityResourcesContraindications Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.