Plaquenil dose based on weight

Discussion in 'Chloroquine Phosphate' started by ru3000, 05-Mar-2020.

  1. Lettie XenForo Moderator

    Plaquenil dose based on weight


    If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female.

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    Any concerns regarding dosage should be discussed with the prescribing physician. Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. For people who weigh less than 80 kg, a lower daily dose is prescribed, up to a maximum of 5 mg/kg of body weight.

    For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day.

    Plaquenil dose based on weight

    Plaquenil Dosage Guide -, Daily Plaquenil Dosage - Crunching Numbers —

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  5. For children and infants, the dose is based on weight. Usually, 5 mg per kg of body weight about 2.3 mg per pound once weekly is recommended, not to exceed the normal adult dosage. Plaquenil comes only in adult-strength tablets, which taste extremely bitter when crushed or chewed.

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    Nov 25, 2019 Alternate dosing based on body weight A total dose representing 25 mg/kg is administered in 3 days, as follows First dose 10 mg base/kg not to exceed 620 mg base orally Second dose 5 mg base/kg not to exceed 310 mg base orally 6 hours after first dose Third dose 5 mg base/kg orally 18 hours after second dose Dec 30, 2015 SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. The recommended dose was subsequently lowered based on the patient’s weight which helps to prevent retinopathy over time. We also request a detailed baseline eye exam which includes color vision and visual field-testing, and repeated every 6-12 months to detect the earliest changes in the retina which may be reversible by stopping or reducing.

     
  6. sslinker New Member

    This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Hydroxychloroquine retinopathy screening Hydroxychloroquine-Induced Retinal Toxicity - American. RCOphth guideline Hydroxychloroquine and Chloroquine.
     
  7. vypik Well-Known Member

    L'artiste belge Stromae a annulé une dizaine de concerts, ses producteurs expliquant ce 14 juin qu’il était "rentré en urgence en Europe" car "les effets secondaires sérieux d'un traitement antipaludique (pris à titre préventif) imposent un suivi médical" qui ne lui permettent pas de "reprendre ses activités pour le moment". Antipaludéens la chloroquine - Effets indésirables. NIVAQUINE - EurekaSanté par VIDAL Contre le coronavirus, des essais "prometteurs" avec la.
     
  8. argo90 XenForo Moderator

    Tizanidine Oral Route Before Using - Mayo Clinic Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Drug Interactions. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.

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