Although I take Enbrel, and MTX, neither one work as well as the Plaquenil and the fatigue and joint pain have returned full force. I had to get off of plaquenil as well b/c of toxicity and benign tumors behind my eyes. I'm just wondering if any of you here have had to stop taking Plaquenil and if so what you replaced it with? Not knowing what your dx is, I don't know what to tell you. I haven't found a replacement except that I started my cytoxan every month now. Plaquenil and alcohol consumption How often is plaquenil taken Adverse effects of plaquenil Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives. First of all, maybe, you should go and see some nutritionist to advise you what kind of food to take. You should eat more of cooking meals, fresh fruit and vegetables and less meat. Natural alternative could be ginger root, nicotine which I wouldn't recommend, papaya and some herbal teas for example. Nothing safer Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. I also seem to be having a lot of anxiety and I never had this before I stopped my Plaq Am I just losing my mind? All I can do is offer you my sympathy and suggest you talk to your rheumy or hope that others here have an answer for you. I found that some of my symtoms came back after I got off of plaquenil too but I never found something to really "replace it" unforntunately. Yes I do get some kind of strange migraines but without the pain??? (If anything) Since stopping it even the sun is now my worst enemy and I have had to get a pair of sun glasses.. Hi momto3, Wow, I hate to hear that you had to stop taking plaquenil. Since you're taking Enbrel and MTX, I suppose you have RA and I can't imagine having that and not being able to take plaquenil. I have suffered with migraines for thirty years and the only true relief I've ever gotten are from accupuncture and immitrex. I've had other problems as well but I don't think those would help you b/c they are more related to SLE. Natural alternatives plaquenil Alternatives to Plaquenil DailyStrength, Natural alternatives to domperidone? Antiemetics Nausea. Plaquenil drug monitoringHow to stop plaquenil tinnitusWallace 1989 chloroquine Compare Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Plaquenil rated 6.8/10 in overall patient satisfaction. Plaquenil Compared to Alternatives - Plaquenil Compared to Alternatives -. Plaquenil substitute - Things You Didn’t Know. Natural Remedies for Treating Lupus. From my research, Plaquenil is one of the most gentle of the disease-modifying drugs, so it's less likely to leave you at risk of infection. One known serious side-effect that happens to something like 1 in 5,000 people after many years of use is that it can cause retinal deposits, which can affect vision. Natural Approaches to Lupus Treatment Alternatives to conventional therapy treatments are becoming more popular due to the inability to find a cure for SLE and a growing desire for a treatment plan carrying a lower risk of adverse side effects. DHEA One alternative therapy gaining acceptance is the use of dehydroepiandrosterone DHEA. The two types of antimalarials most often prescribed today for lupus are hydroxychloroquine Plaquenil® and chloroquine Aralen®. Unlike the rapid response seen with steroids, it may take months before antimalarial drugs improve your lupus symptoms. Side effects from antimalarials are rare and usually mild.