Chloroquine in early pregnancy

Discussion in 'Chloroquine Phosphate' started by ElenaKa, 03-Mar-2020.

  1. Cashemir Well-Known Member

    Chloroquine in early pregnancy


    This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus.

    How does chloroquine kill the malaria parasite Plaquenil efectos secundarios

    In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. It does not appear to be safe during pregnancy. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. Currently, there are no viable treatment options to prevent the spread of ZIKV. However, in a study by Delvecchio et al. 2016, 17 the potential for the antimalarial agent chloroquine CQ to inhibit the endocytosis of ZIKV within human brain microvascular endothelial and neural stem cells was demonstrated in vitro.

    For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®.

    Chloroquine in early pregnancy

    Prophylactic use of antimalarials during pregnancy, Hydroxychloroquine - Wikipedia

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  4. Chloroquine and mefloquine are the drugs of choice for pregnant women for destinations with chloroquine-sensitive and chloroquine-resistant malaria, respectively. Doxycycline is contraindicated because of teratogenic effects on the fetus after the fourth month of pregnancy.

    • Pregnant Travelers - Chapter 7 - 2020 Yellow Book..
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    • Treatment of SLE in pregnancy and use of Chloroquine The BMJ.

    Find out whether it’s a safe option during pregnancy, discover guidelines for women with RA who are trying to conceive, and more. If you’re pregnant and have rheumatoid arthritis RA, you may. Chloroquine, extensively used in pregnancy, is generally thought to be safe for mother and fetus at the therapeutically recommended dose.2 Treatment of Plasmodium falciparum malaria in pregnancy in Kenya3 and Tanzania 4 have indicated the drug to be safe, although with the problem of treatment failure because of parasite resistance. For pregnant women diagnosed with uncomplicated malaria caused by chloroquine-resistant P. falciparum infection, women in the second and third trimesters can be treated with artemether-lumfantrine, and for all trimesters, mefloquine or a combination of quinine sulfate and clindamycin is recommended. Quinine treatment should continue for 7 days for infections acquired in Southeast Asia and for 3 days for infections acquired elsewhere; clindamycin treatment should continue for 7 days.

     
  5. Erazm Hemul Well-Known Member

    Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. Plaquenil Uses, Dosage & Side Effects - Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil Hydroxychloroquine - Side Effects, Dosage.
     
  6. A I F XenForo Moderator

    studies also provide the percentage of patients positive on day 3, which is an indicator of parasite susceptibility to the artemisinin component of an artemisinin-based combination therapy (ACT). Treatment_of_malaria TUSOM Pharmwiki Chloroquine - StatPearls - NCBI Bookshelf Chloroquine-Sensitive Malaria –
     
  7. Vik78 Guest

    Artemisinin - Molecule of the Month May 2013 - HTML-only. Artemisinin itself, the active molecule, was isolated in 1972. When its structure was determined in 1975, it was found that its activity stemmed from a novel endoperoxide bridge. For some years artemisinin was not known in the West, until it was revealed at a conference in 1981.

    Genetic architecture of artemisinin-resistant Plasmodium.
     
  8. ID1 Well-Known Member

    Chloroquine and Cancer Treatment - Biomedical Research, A. Pancreatic cancer is highly lethal disease. It is estimated that in 2010 more than 43,000 individuals in the United States have been diagnosed with this condition, and 36,800 have died from the disease. Most of these tumors tend to be therapeutically resistant against cytotoxic chemotherapies, targeted agents, and radiotherapy.

    Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a.