Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Can you use plaquenil if allergic to quinine Chloroquine and proguanil Gi problems with hydroxychloroquine Hyperpigmentation occurs when a person develops darker patches on the skin, such as age spots or melasma. Learn about the causes, types, and treatments for hyperpigmentation here. The treatment for porphyria cutanea tarda focuses on managing and stopping the symptoms. Lifestyle changes, such as limiting alcohol consumption and not smoking, may also help. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Treatment of plaquenil hyperpigmentation Skin Pigmentation with Hydroxychloroquine Plaquenil — Donovan Hair Clinic, Porphyria Cutanea Tarda Pictures, Treatment, and More Is aralen safe for pregnancyWhat do hydroxychloroquine doDiscoid lupus and plaquenil Home August 2013 - Volume 19 - Issue 5 Hydroxychloroquine-Induced Hyperpigmentation. Log in to view full text. If you're not a subscriber, you can You can read the full text of this article if you-- Select an option -- Log In Buy This Article Become a Subscriber Hydroxychloroquine-Induced Hyperpigmentation JCR.. Skin Discoloration and Plaquenil - Arthritis Information. Will you have Skin hyperpigmentation with Plaquenil - eHealthMe. Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. A total of 41 patients 38 women and 3 men were included in the study. The mean age was 39.2 ± 15.4 years. The hydroxychloroquine was indicated for systemic lupus erythematosus in 73.2%, dermatomyositis in 12.2%, rheumatoid arthritis in 9.8%, actinic lichen and sarcoidosis each in 2.4%. I think it's due to Hydroxycholoroquine-induced hyperpigmentation an example of drug-induced skin pigmentation. I thought it worth showing those of you on the medication. Why is it so much worse on the right forearm? Well she's only just started to drive again.