Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil antimalarial medications Can i take plaquenil and methotrexate together Plaquenil and thyroid Chloroquine over the counter uk Drugs used in chemotherapy, such as hydroxychloroquine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving trametinib together with hydroxychloroquine may work better in treating patients with pancreatic cancer. Hydroxychloroquine and trametinib are approved by the Food and Drug Administration for the treatment of malaria and melanoma, respectively. In compliance with ethical guidelines, Dr. Kinsey offered the patient compassionate use and off-label treatment with trametinib and hydroxychloroquine, and the patient accepted. Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer THREAD The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Trametinib hydroxychloroquine Trametinib and Hydroxychloroquine in Treating Patients with., Hitting an Elusive Target in Pancreatic Cancer - National. How long plaquenil take to work This phase I / II trial studies the side effects and best dose of hydroxychloroquine when given together with dabrafenib and trametinib and to see how well they work in treating patients with stage IV melanoma that has spread to other places in the body. Dabrafenib, Trametinib and Hydroxychloroquine in Treating Patients with.. Trametinib and Hydroxychloroquine in Treating Patients.. MEK and Autophagy Inhibition in Metastatic/Locally.. Trametinib and Hydroxychloroquine in Treating Patients with Pancreatic Cancer THREAD University of Utah / Novartis Pharmaceuticals Identifier NCT03825289 Trametinib PubChem CID 11707110 Huntsman Cancer Institute, University of Utah Photo National Cancer Institute Investigators at the Huntsman Cancer Institute at the University of Utah are conducting a Phase I clinical. Trametinib and dabrafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving hydroxychloroquine with trametinib and/or dabrafenib may lower the chance of brain tumors from growing or spreading compared to usual treatments. Dabrafenib, Trametinib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma BAMM The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government.