Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Nivaquine p chloroquine phosphate Chloroquine resistant area cdc Cardiomyopathy is a progressive disease of the myocardium, or heart muscle. In most cases, the heart muscle weakens and is unable to pump blood to the rest of the body as well as it should. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Cardiac Effects, including Cardiomyopathy and QT prolongation Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of PLAQUENIL as well as with use of chloroquine. Patients may present with atrioventricular block, pulmonary hypertension, sick sinus syndrome or with cardiac complications. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil related cardiomyopathy Hydroxychloroquine Induced Cardiotoxicity A Rare., Hydroxychloroquine Plaquenil Hydroxychloroquine to stop flare ups In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. PLAQUENIL® HYDROXYCHLOROQUINE SULFATE TABLETS, USP. Cardiomyopathy - Symptoms and causes - Mayo Clinic. The differential diagnosis for left ventricular dysfunction in systemic lupus erythematosus patients is wide and includes coronary artery disease, myocarditis, and valvular disease. This case illustrates the importance of also considering hydroxychloroquine toxicity, as it can be reversed by cessation of the drug. Chloroquine CQ and hydroxychloroquine HCQ are anti‐rheumatic medications frequently used in the treatment of connective tissue disorders. We present the case of a 45‐year‐old woman with CQ‐induced cardiomyopathy leading to severe heart failure. HYDROXYCHLOROQUINE PLAQUENIL CARDIOTOXICITY AN UNCOMMON COMPLICATION OF A COMMON MEDICATION. Your Name has forwarded a page to you from JACC Journal of the American College of Cardiology. Your Name thought you would like to see this page from the JACC Journal of the American College of Cardiology web site.