B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Plaquenil maculopathy management Chloroquine long qt Plaquenil con alcohol Benlysta vs plaquenil Plaquenil and Increased tendency to bruise - from FDA reports Summary Increased tendency to bruise is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Osteoporosis. I've started to get really tender shins and bruising for no reason on my legs. I've seen my gp and they are miffed and have done some blood tests. I have alot of fatigue and my legs feel heavy, im on plaquenil and nifidipine for raynauds. has anyone else had this? Then my dogs kept running into my shin on that same leg. Now my leg is this weird grayish purple color. doc says plaquenil causes the blood, that would normally dissipate, to stay in the skin cells, thus changing the pigmentation of the skin. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Bruising on shin from plaquenil Has anyone taking Plaquenil ever experienced bruising under., Unexplained bruising DailyStrength Why is chloroquine used to treat lupusOct mac plaquenil saucerPlaquenil medscape Plaquenil, systemic lupus erythematosus, bruising, skin. I have been taking the drug for almost two year for Sjogrens syndrome/lupus and recently I have noticed unexplainable brusing on my back and thighs. Has anyone taking Plaquenil ever experienced bruising.. Discloration / Bruising / Age Spots on Head" Lupus.. Erythema Nodosum Symptoms, Causes, Diagnosis, and Treatment. Feb 19, 2020 What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Hyperpigmentation of skin, mucosa, and nails can be observed in patients treated with antimalarials, including hydroxychloroquine. Elder abuse is a significant and underreported problem in seniors. Cutaneous findings can aid in the discovery of physical abuse, sexual abuse, and self-neglect in elderly individuals. I’ve been on plaquenil for about 1.5 months now and I’m noticing I’ve been bruising so easily. I’ve always bruised pretty easily but they’re fairly superficial bruises, not very painful, and go away pretty quickly. These new bruises that have showed up these past few weeks are a whole different story.