But there's evidence the drug can activate a virus that can increase the risk of lymphoma and similar cancers in some patients. A number of reports have linked methotrexate with lymphoma and similar cancers of the lymph glands, says senior researcher Shannon C. Kenney, MD, a microbiologist and infectious disease specialist with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill. Plaquenil and parkinson's Plaquenil rp Hydroxychloroquine online perscriptipn Learn about drug interactions between hydroxychloroquine oral and methotrexate sodium oral and use the RxList drug interaction checker to check drug combinations. Coadministration of hydroxychloroquine sulfate with other antimalarials known to lower the convulsion threshold e.g. mefloquine may increase the risk of convulsions. Antiepileptics The activity of antiepileptic drugs might be impaired if coadministered with hydroxychloroquine sulfate. Methotrexate Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. This risk may increase if. Some studies have indicated that the drug's immune-weakening effect places people at risk for viral-associated lymphomas. Also, studies have shown that when rheumatoid arthritis patients quit taking methotrexate, their lymphoma went into regression, another sign that the drug directly contributes to the cancer, she tells Web MD. Hydroxychloroquine increse methotrexate Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Hydroxychloroquine Tablets - FDA prescribing information. Is plaquenil used to treat psoriatic arthritis Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Side-effects, uses, time to work. For people with rheumatoid arthritis, methotrexate is the treatment of choice in reducing pain and inflammation. But there's evidence the drug can activate a virus that can increase the risk of. Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Reduces inflammation and cell replication. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects.