Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil missed dose Chloroquine treatment of cells Chloroquine toxicity antidote Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week. Plaquenil is also known as a treatment for malaria, a blood-borne parasite spread by mosquitoes in many tropical and sub-tropical environments. Taking Plaquenil. Plaquenil is available in 200 mg oral tablets. The usual dose is between one and two tablets per day 200 to 400 mg per day. I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. I take my plaquenil with my evening meal. When is the best time to take it? Would it be best in the morning? I also take in the morning thyroxine, omeprazole and co-codamol, would it interfere with any of those if I took it in the morning instead of. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. How to take plaquenil 200 mg Taking Plaquenil for Rheumatoid Arthritis, Plaquenil – RheumInfo Chloroquine diphosphate autophagy I take 200 mg in the morning after I eat and 200 mg in the evening after eating. When I first started Plaquenil Nov. 2001, the pharmacist recommended taking it after a meal, saying it can bother you if your stomach is empty. I've been fine doing it this way. How do you take Plaquenil?. When best time of day to take plaquenil? - LUPUS UK. Taking Plaquenil for Various Conditions and Treatment Tips. The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Systemic lupus erythematosus is treated with 400 mg once or twice daily for several weeks then 200-400 mg daily. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works.