I thought it was a sulfa drug or at least in the same class. I would have thought that the "sulfate" in the name would be a give away? Tumors associated with plaquenil Hydroxychloroquine liver talks Chloroquine cytokine Back in April i started to take the Brand Plaquenil because I am allergic to Sulfa. I had read that it was better to take the Brand if you were allergic to Sulfa. And thank goodness, I have done well with it so far. I was started on a small dose, 1\2 tablet a day, but now the Rheumie wants me to take 400 mg a day. PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Other medications that may cause a reaction. Other types of sulfa medications may trigger a reaction in some people who have a sulfa allergy Sulfasalazine Azulfidine, used to treat Crohn's disease, ulcerative colitis and rheumatoid arthritis. Dapsone, used to treat leprosy, dermatitis and certain types of pneumonia. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. The active components are bound to a sulphur compound as it slows down release times compared to hydrogen chloride which are usually found in faster release medications. what you are allergic to is sulfonamides like bactrim, right? Sulfate used after a drug name is just the last name of the chemical, its the sulfate salt. Is plaquenil a sulfonamide Plaquenil hydroxychloroquine Alternatives & Similar., Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Statistics about chloroquine Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Plaquenil Oral Interactions with Other Medication. Sulfa allergy Which medications should I avoid? - Mayo Clinic. Another Plaquenil Question DailyStrength. Answer - Posted in allergic reactions, hydroxychloroquine - Answer They aren't related in any way. These are not sulfates. Sulfate used after a drug name is just the last name of the chemical, its the sulfate salt. It has nothing to do with sulfonamides. Allergy to sulfonamide antibiotics has no relationship to allergies to hydroxychloroquine. Plaquenil Description Plaquenil ® hydroxychloroquine sulfate is a white or practically white, crystalline powder, freely soluble in water; practically insoluble in alcohol, chloroform, and in ether. The chemical name for hydroxychloroquine sulfate is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11.