Its cause is not known, and most episodes of granuloma annulare clear up after a few years, with or without treatment. Although granuloma annulare can occur in people of any race and at any age, it is most commonly seen in children and young adults. Hydroxychloroquine itchy skin Chloroquine phosphate malaria prophylaxis Figure caption and citation for the preceding image starts Classic localized granuloma annulare From the collection of Susmita Mukherjee, BSc, MBBS, MRCP; used with permission Citation ends. A number of clinical variants exist. Piette EW, Rosenbach M. Granuloma annulare clinical and histologic variants, epidemiology, and genetics. Granuloma annulare is a common and benign skin condition that produces ring-shaped lesions, generally on the hands and feet. Its exact causes are unknown. Although there is no known cure and it generally self-resolves, dermatologists may recommend various treatments to alleviate the symptoms. Granuloma annulare of the-wrist and forearms developed in a 62-year-old woman in August 1992. She was examined at Mayo Clinic Rochester, and the results of two skin biopsies confirmed the diagnosis. A topically applied corticosteroid cream was not helpful. For 2 months thereafter, granuloma annulare lesions involved her hands and fingers. The lesions of granuloma annulare are usually found in the same areas on both sides of the body (symmetrically). Females are slightly more likely than males to develop granuloma annulare. Chloroquin andgranuloma annulare Granuloma Annulare - Pictures, Causes, Contagious, Symptoms, Treatment., Granuloma Annulare Symptoms, Causes, and Treatment Options Plaquenil 中文John hopkins research on plaquenilHydroxychloroquine for psoriasisHow plaquenil works for sjogrensDoes plaquenil treat inflammation There are other less common forms of granuloma annulare Generalised granuloma annulare 8-15% of cases. Adults are more commonly affected. It is characterised by widespread small bumps or discoloured patches of skin, with a tendency to present on the trunk. Subcutaneous granuloma annulare is rare. It is more commonly seen in children. ACD A-Z of Skin - Granuloma annulare. Successful Treatment Response of Granuloma Annulare and.. Disseminated Granuloma Annulare Report of a Case Treated.. Granuloma annulare GA is skin disorder that most often causes a rash with red bumps erythematous papules arranged in a circle or ring pattern annular. GA is not contagious and is not cancerous. The rash may be localized or generalized. While there is limited evidence for their use in this indication, antimalarial agents e.g. hydroxychloroquine or chloroquine are the most widely supported and most often used first-line drugs. Grewal SK, Rubin C, Rosenbach M. Antimalarial therapy for granuloma annulare results of a retrospective analysis. Treatment. Treatment usually isn't needed for granuloma annulare. Most bumps disappear in a few months and rarely last more than two years. But if you're bothered by how your skin looks or feels, ask your doctor about treatment, which can help them disappear faster.