Monitoring hydroxychloroquine

Discussion in 'Canada Drugs Online' started by Beirut, 16-Mar-2020.

  1. Fabi1976 Well-Known Member

    Monitoring hydroxychloroquine


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Monitoring tests, but that monitoring begins after one year of therapy for all patients on chloroquine. Monitoring may be best incorporated into the hospital eye service via virtual clinics. The results of monitoring should be communicated back to the prescribing doctor, patient and GP as normal, possible or definite hydroxychloroquine retinopathy. Side effectsManagementGoalsMechanismPrognosisPathophysiologyToxicityPreventionInteractionsGeneticsPurposeMedical usesAnalysisResearchDiagnosisSecurityResourcesContraindications Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Monitoring hydroxychloroquine

    Hydroxychloroquine Professional Patient Advice -, Recommendations on Screening for Chloroquine

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  4. Hydroxychloroquine for more than five years and/or in high doses are at increased risk of damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as retinal toxicity or retinopathy. Overall, around seven patients out of every 100 taking hydroxychloroquine

    • Eye screening for patients taking hydroxychloroquine..
    • Recommendations on Screening for Chloroquine and..
    • Monitoring and Preventing Hydroxychloroquine, Plaquenil..

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil hydroxycholoroquine is a medication used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions. It is very effective and the risk of damage to the eye is very low the first five years if the patient is receiving the recommended dose and does not have special risk factors like kidney damage. The new guideline on screening for hydroxychloroquine and chloroquine retinopathy is written in response to evidence from the United States that shows that hydroxychloroquine retinopathy is more common than previously recognised. Implementation of the guideline’s recommendations will prevent iatrogenic visual loss.

     
  5. nickolaza Moderator

    500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart. Drug resistance in malaria Malaria Health Information for International Travel Chloroquine-Resistant Malaria The Journal of Infectious.
     
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