Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. Dermatomyositis rash and plaquenil How common is chloroquine retinopathy Why chloroquine start with loading dose Rheumatoid arthirtis methrotrexate therapy hydroxychloroquine monotherapy Mar 17, 2020 Drug information on Hydroxychloroquine sulfate for health care professionals. Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. Hydroxychloroquine sulfate molecular weight Hydroxychloroquine Sulfate C18H28ClN3O5S ChemSpider, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Is plaquenil used for mixed connectivity tissue disorder CAS 747-36-4 Molecular Formula C 18 H 26 ClN 3 OH 2 SO 4 Molecular Weight g/mol 433.96 MDL Number MFCD00078203 InChI Key JCBIVZZPXRZKTI-UHFFFAOYSA-N Synonym hydroxychloroquine sulfate,hydroxychloroquine sulphate,ercoquin,plaquinol,toremonil,2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate,hydroxychloroquine sulfate usp,plaquenil tn,hydroxychloroquine; sulfuric. Hydroxychloroquine sulfate, 98%, ACROS Organics Fisher.. Hydroxychloroquine Sulfate CAS. Plaquenil - FDA prescribing information, side effects and uses. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine Sulfate, 747-36-4 Hydroxychloroquine C18H26ClN3O CID 3652 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities.