It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Warfarin interaction with hydroxychloroquin Cyp2d6 and plaquenil Plaquenil not working what next Jun 13, 2016 A total dose representing 25 mg of base per kg of body weight is administered in three days, as follows First dose 10 mg base per kg but not exceeding a single dose of 620 mg base. Second dose 5 mg base per kg but not exceeding a single dose of 310 mg base 6 hours after first dose. Third dose 5 mg base per kg 18 hours after second dose. However, in general terms, taking 400 mg of hydroxychloroquine is within a safe range for most people. In fact, for some people, this will be the dose they are prescribed. Jeff Donovan MD PhD FRCPC FAAD US & Canadian board-certified Dermatologist Toronto, Canada I accidentally have taken 2-3 extra doses of my thyroid medication the last few days. Should I skip a day take a dose and skip another day? I'm in the process of cutting down the dosage due to surgery 18 month ago. I have gone from 175 to 112 and it still needs to go lower as I'm way over medicated. This how I messed up. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Accidental double dose of plaquenil Levaquin Overdose - Antibiotics Home Page, I accidentally took two 200mg tabs of hydroxychloroquine. Chloroquine during early pregnancyPlaquenil dosisOrder aralen 500mgHydroxychloroquine narcoticChloroquine and proguanil Hydroxychloroquine has also been used as therapy of porphyria cutanea tarda where it seems to act by increasing excretion of porphyrins. Hydroxychloroquine is available in generic forms and under the brand names of Plaquenil in tablets of 200 mg. The usual dose is 400 mg daily in one or two divided doses. Hydroxychloroquine - LiverTox - NCBI Bookshelf. Accidentally took too much Levthroxinegeneric synthroid?. What should I do if I accidentally take an extra dose of.. Hydroxychloroquine overdose using high dose diazepam therapy, the mortality was 50%. The case ingesting the greatest dose of 22 g survived without utilising any diazepam. Further studies on the benefits of high dose benzodiazepine therapy have yet to be done. The hypokalemia is thought to be secondary to potassium channel blockage causing over-dominant Usual Adult Dose for Malaria Prophylaxis. Suppression 400 mg 310 mg base orally on the same day every week Comments-Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 800 mg 620 mg base may be taken in 2 divided doses 6 hours apart. Caution is advised when using Plaquenil in children because they may be more sensitive to the side effects of the drug. Plaquenil is not recommended for long-term use in children. If a child accidentally takes Plaquenil, even a small amount can be very harmful possibly fatal. Be sure to keep Plaquenil out of the reach of children.