Suddenly I'm experiencing eye problems (blilnd spots). I have stopped taking plaquenil, but now I'm being told by doctors that the damage is not necessarily reversible especially if you have taken it for a long time. Hydroxychloroquine sulfa allergy Hydroxychloroquine and infertility Does plaquenil make an infection worse Chloroquine and piriton Currently, one of the primary functional screening tests recommended for the evaluation of Plaquenil retinal toxicity is 10-2 white stimulus automated visual fields; however, research shows Asian patients benefited from 24-2 or 30-2 visual fields, given that toxicity often manifests changes beyond the macula in these patients. 9 Because. Is Damage Still Occurring? Can Plaquenil macular toxicity continue to progress long after the patient stops taking the drug. and foveal thickness measurements served as the standard metrics on SD-OCT testing. Sfikakis PP, Mavrikakis E, et al. The incidence of irreversible retinal toxicity in patients treated with hydroxychloroquine a. Retinal toxicity has been shown in patients taking greater than 3 mg/kg/day of chloroquine or 6.5 mg/kg/day of hydroxychloroquine. While most cases of toxicity have been reported for chloroquine, hydroxychloroquine has supplanted it as the more commonly used treatment agent for both RA and SLE. 2 My mother was diagnosed with Plaquenil Toxicity in 2007 she first noticed changes in 2006, although being followed by her eye doctor they failed to notice this as Plaquenil TX until it was to late. I'm hoping to find people who have recovered from the eye damage. Retinal thickness map plaquenil toxicity Plaquenil Toxicity - Bulls Eye Maculopathy - Retina Gallery., Is Damage Still Occurring? - Review of Optometry Does plaquenil make you sun sensitiveLife extension chloroquinePlaquenil weight lossHydroxychloroquine manufacturer Aug 01, 2009 I just went to Winston-Salem to see a retinal specialist and am waiting for his reply--he did say it looked suspicious for toxicity. I just read an article by a lady who has experienced the same visual disturbances and was diagnosed with toxicity and has been off plaquenil 2 years but her eyes are still getting worse. Has anyone experienced plaquenil toxicity with damage to eyes?. Common Medications That May Be Toxic to the Retina. Retinal Physician - Appropriate Interpretation of OCT Imaging. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Macular thickness map on CIRRUS OCT;. Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the. To date, several investigators have used SD-OCT in eyes with HCQ toxicity and qualitatively evaluated thinning of the outer retinal layers or attenuation of the ellipsoid zone EZ, while others have quantitatively analysed outer retinal thickness on SD-OCT topographic map.7–10 This study aims to characterise HCQ toxicity using a newly.