Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine for dogs Hydroxychloroquine and tylenol Plaquenil side effects depression I have taken plaquenil for lupus off and on for two years one day I started having panic attacks I stopped caffeine alcohol etc. The only thing that helped was stopping the plaquenil after feeling better and some time I thought I’d try it again after a flare. First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. When I started taking Plaquenil, I got a bit depressed but that's not a big deal. If diarrhea came back I had to back off and wait a week to add it again. After 2 months I could take the full dose BUT I can't take it as one tablet in a.m. and one in p.m. I have to break it up and take it 4 times a day to get in the normal 2 200mg tablets per day. The dizziness got better although I still have it a little from time to time. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil cause dizziness after 2 years Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, PLAQUENIL Side Effects, Reviews by Patients - Hydroxychloroquine sulfate 200 mg patient information leafletHydroxychloroquine withdrawal Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil and dizziness DailyStrength. Irritability and increased hot flashes with Plaquenil. Oct 18, 2005 I was on Plaquenil for 6 years with almost no side effects. However, after going off for about 2 years while they investigated the cause of eye problemsnot Plaquenil I had a lot of side effects when I re-started, including eye problems and had to stop the drug. So it can cause different things at different times to different people. Can plaquenil hydroxychloroquine cause a blistering rash on palms of hands. Is that a common side affect. I am also vomiting everyday. How long does it take for plaquenil hydroxychloroquine to work with rashes? Plaquenil hydroxychloroquine has brought ANA, SED, C-Reactive down. I function-barely. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. It was the worst 2 months of these side effects I've ever had in my life! Got off of it and I feel back to normal.