Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Chloroquine for sale Chloroquine intercalating dna Chloroquine fas associated Plaquenil is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. Plaquenil is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations of Use in Malaria • Plaquenil is not recommended for the treatment of complicated malaria. Hydroxychloroquine Why you need an eye exam March 09, 2017 / Stonewire Optometry / Stonewire Optometry Hydroxychloroquine Plaquenil was originally a medication used to help prevent and treat malaria but was later discovered to have positive effects on autoimmune conditions as well. This test involves injecting dye into the arm followed by photographs of the back of the eye. Hydroxychloroquine damage can show up as a ring of damage around the central part of vision. If any problems are identified with testing at the hospital, you will be contacted directly by the ophthalmologist or a member of the eye care team. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Eye test for plaquenil toxicity frequency Plaquenil Updates eyeupdate, Stonewire Optometry-Blog-Hydroxychloroquine Why you need an eye exam Plaquenil and diabetesEye exam when taking plaquenilDo the side effects of plaquenil go awayPsoriasis from generic plaquenilHydroxychloroquine sulfate painkiller Plaquenil and eye exams allie_bf posted For the last few years, my rheumagologist and opthamologist have disagreed on the frequency for eye exams my opthamologist says every year is sufficient, but my rheumatologist still insists every 6 months is what should be done. Plaquenil and eye exams" Lupus Community - Support Group. Plaquenil Toxicity - alberta-. H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS. The risk of a toxicity sharply increases after 5 years, with majority of cases of retinotoxicity occurring in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Risk of Toxicity The risk of toxicity is dependent on daily dose and duration of use. At recommended doses, the risk of toxicity up to 5 years is under 1% and up to 10 years is under 2%.