Chloroquine lupus erythematosus

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  1. Chipus Moderator

    Chloroquine lupus erythematosus


    Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality.

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    Systemic lupus erythematosus SLE is an autoimmune disease with a complex pathogenesis. Published data have revealed that serum levels of proinflammatory cytokines are increased in SLE patients. The aim of our study was to evaluate whether monotherapy with chloroquine phosphate affects IL-1beta, IL-6, IL-18 and TNF-alpha serum levels in SLE. Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy. Jul 30, 2019 Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy.

    Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids.

    Chloroquine lupus erythematosus

    Systemic Lupus Erythematosus Symptoms, Treatment., Chloroquine Side Effects Common, Severe, Long Term.

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  6. Systemic lupus erythematosus is a multisystem inflammatory disease that is often difficult to diagnose. Before the diagnosis can be established, four of 11 clinical and laboratory criteria must be.

    • Diagnosis of Systemic Lupus Erythematosus.
    • Chloroquine Side Effects Common, Severe, Long Term -.
    • Chloroquine C18H26ClN3 - PubChem.

    Subacute cutaneous lupus erythematosus SCLE is a nonscarring, non–atrophy-producing, photosensitive dermatosis. SCLE commonly develops in sun-exposed areas, including the upper back, shoulders, extensor arms, neck, and upper torso, while the face is often spared. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition.

     
  7. Himera Guest

    Since being diagnosed with Lupus and taking the normal meds, particularly Plaquenil and Prednisone (over about 6 years), I gained about 45 pounds. Hydroxychloroquine - Side Effects, Dosage, Interactions. Rx Side Effects New Plaquenil Guidelines and More. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  8. ORiON4 Guest

    AMERICAN COLLEGE OF RHEUMATOLOGY Factors for toxicity related to hydroxychloroquine use. BACKGROUND 1 Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term 2 management of a variety of chronic rheumatic diseases including systemic lupus erythematosus 3 and rheumatoid arthritis. A range of potential toxicities related to HCQ use have been reported

    Hydroxychloroquine Plaquenil Success, Reviews and Side Effects
     
  9. Alexiy2 Well-Known Member

    Hydroxychloroquine User Reviews for Lyme Disease. Plaquenil hydroxychloroquine "I felt better than I have in 20 years! After 20 years on NSAIDS needed for Lyme arthritis, my kidneys were affected, and when I stopped NSAIDS cold turkey, it was amazing how much pain my body was in. Now a year into Plaquenil I feel like a new person. Get eyes checked every 6 months.

    Clarithromycin and hydroxychloroquine Plaquenil - LymeNet Europe