As a result, the body produces antibodies that inflict cell damage, most commonly targeting joints, skin, kidneys and the nervous system. I think even though they say it doesn't make a difference, I feel wierd if I don't take my plaquenil sometimes. Hi want2bepainfree, If you don't have to, don't stop your plaquenil. No one knows but I cry sometimes when no one is around to see me. Hugs, Mel Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. Join the group and find support for coping with lupus. I stopped taking the plaquenil the beginning of December. And when I'm crying like a baby--I could feel the pain just throb in me. I took plaquenil for several years, then I went to the Mayo Clinic and they didn't think I had lupus and took me off. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Facts on chloroquine Plaquenil and parkinson's What medicines target same receptors as plaquenil Medical professionals do not recommend stopping percocet cold turkey abruptly. Going cold turkey off Percocet can result in severe pain and health complications. Medical professionals recommend that instead of quitting cold turkey you get tapered off percocet over the course of a few weeks by lowering the dosage. Aug 26, 2016 He said that I could stop plaquenil cold turkey. It slowly decreases effectiveness in the body. After the holidays, I am tempted to stop to see if the symptoms of lupus reappear so he can diagnose me. A lower dose may stop them. Do not lower the dose on your own. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. It doesn't agree with my stomach (I take it with meals too). The pain in my swollen neck glands is horrific, and my arms and legs are hurting once again. Why does it seem like my whole life just turned for the worst --it was like I was fine one day and the next I'm so ill. It was pure hell, every joint in my body hurt and the fatigue was tremendous. As Tracy stated it is such as slow acting drug when you first start it, it's really hard to tell if it's working, it's not until we stop the med that we realize what a huge difference it was making. I happen to run out of my medication and fail to be in a hurry to get a refill because I had convinced myself that it wasn't working anyway. I missed 2 doses and felt a lot of pain in my arms, and had a pretty bad couple of days. Just wondering if any of you experience any pain if you don't take a few pills. Can you stop hydroxychloroquine cold turkey Alcohol Withdrawal Cold Turkey Dangers, Stopping Plaquenil - General Discussion - Life With Lupus Hydroxychloroquine male fertilityChloroquine diphospahe bbguyFda chloroquine-primaquine pill malariaCan hydroxychloroquine cause pancreatitisChloroquine and lc3 Lawchick my name is chellety and yes i have had horrbile side effects with the plaquenil they say it is suppose to be the best medication you can use for lupus but i was getting symptoms of that of a diabetes patient like gout in my toe, it was horrible pain and burning OMG, sounds weird but i stop taking the plaquenil and stuck to predisone. Had to stop taking Plaquenil -. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. What happens when a diabetic 2, stops cold turkey taking.. Can you stop Plaquenil cold turkey" answer - YES. My rheumy told me to take time out on it for a month once. I really don't know why because he only told me to do it the once and I've been on it for six years now He said to give the system a rest for a moth and siad in his experience the disease seemed to be less active in January - so to do it then. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. I can't believe you were told to stop taking plaquenil after only 6 months since it can take up to one YEAR to achieve full benefits! I don't know much about any sort of withdrawal but if I were you I'd start taking it again. I'd also have your thyroid checked. I'm hypothyroid and take levo along with he plaquenil.